The GHCSS Has Concluded
The Global Health Clinical Seminar Series ran from 2007–2012 and was supported through PEPFAR, the President's Emergency Plan for AIDS Relief. It was produced by International Training & Education Center on HIV (I-TECH) with funding from Cooperative Agreement U91HA06801 from the U.S. Department of Health and Human Services, Health Resources and Services Administration (HRSA), in collaboration with CDC.
Issues in Isoniazid Preventive Therapy: Durability, Duration, Secondary Prophylaxis
Isoniazid preventive treatment is one of the cornerstones of TB prevention, especially in settings with a high burden of HIV and endemic TB. Recent studies have raised questions about the durability of protection, the optimal length of isoniazid treatment, and the benefit of other regimens to treat latent TB infection. We will review original research findings addressing long term effectiveness of IPT in Namibia and some other studies in similar health care settings which have high rates of TB/HIV co-infection. We will also discuss secondary isoniazid prophylaxis for prevention of TB recurrence in people living with HIV.
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